Method Development for Analysis of  Amphetamine-type Drugs Using Gc-ms: Forensic Toxicology & Drugs Abuse - Mahesh Sharma - Books - LAP LAMBERT Academic Publishing - 9783659452673 - October 25, 2013
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Method Development for Analysis of Amphetamine-type Drugs Using Gc-ms: Forensic Toxicology & Drugs Abuse

Mahesh Sharma

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Method Development for Analysis of Amphetamine-type Drugs Using Gc-ms: Forensic Toxicology & Drugs Abuse

Forensic toxicology is the application of toxicology to the matter of law. This work is based on forensic drug testing field of forensic toxicology. Nowadays, the abusing of drugs is considered as a very intense problem which occurring in communities. More and more people are getting addicted to drugs and many are the drug dealers. The main purpose of the present study was the drug profiling and identification of eight Amphetamine-type stimulants (d-amphetamine sulphate, (+)-methamphetamine, Ibuprofen, Piperazine hexahydrate, 1-(4-methoxyphenyl) piperazine, 1-(4-trifluoromethylphenyl) piperazine, 1-Benzylpiperazine and 1-(2-methoxyphenyl) piperazine) by developing a GC-MS method which would detect all the above drugs at the same time. Quinoline was used as internal standard (IS) during the present GC-MS analysis. The first step was the individual drug analysis by the developed GC-MS method and the next step was the mixed drug analysis. The drugs were derivatised by the acylation reagent PFPA, however the silylation reagent BSTFA: TMCS (99:1) was also used as an alternative to acylation. The standard curve of each drug was plotted and the LOD & LOQ was calculated.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released October 25, 2013
ISBN13 9783659452673
Publishers LAP LAMBERT Academic Publishing
Pages 108
Dimensions 150 × 7 × 226 mm   ·   179 g
Language German  

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